Senior Director, Global Tax Planning

Job Title: Senior Director, Global Tax PlanningJob Location: Remote (US)Job Location Type: RemoteJob Contract Type: Full-timeJob Seniority Level: BeOne continues to grow at a rapid pace with challenging and exciting opportunities for experienced professionals. When considering candidates, we look for scientific and business professionals who are highly motivated, collaborative, and most importantly, share our passionate interest in fighting cancer.General Description:The Senior Director, Global Tax Planning will advance the company’s global tax strategy in support of its mission to discover and develop innovative oncology treatments. This role leads complex cross‑border planning initiatives and develops tax‑efficient structures for intellectual property, R&D operations, clinical trial activities, global supply chain, and commercialization. The Senior Director ensures alignment with business strategy while maintaining compliance with rapidly evolving global tax regulations including OECD Pillar Two and upholding strong governance across intellectual property, transfer pricing, and global incentive regimes.Essential Functions of the Job: Global Tax Strategy & Planning Develop and implement the company’s global tax planning roadmap to optimize the effective tax rate, cash tax position, and capital allocation. Design international tax structures supporting global R&D activities, oncology clinical trials, manufacturing networks (including CDMOs), and worldwide commercialization. Evaluate tax impacts of global expansion, new market entry, commercial launches, and evolving regulatory guidance. Lead strategic IP planning, including IP ownership, development, cost‑sharing, and technology transfer strategies aligned with value creation. Cross‑Border Transactions & Structuring Lead tax structuring for mergers, acquisitions, licensing agreements, joint ventures, and strategic collaborations. Conduct tax due diligence, model tax outcomes, and drive integration planning for acquired entities or assets. Analyze and structure intercompany financing, capital flows, and treasury‑related initiatives to ensure efficiency and compliance. Transfer Pricing & Value Chain Optimization Oversee global transfer pricing strategy and ensure alignment with the company’s operating model across discovery, clinical development, manufacturing, and commercialization. Establish and manage intercompany agreements, TP documentation, and local‑file/master‑file requirements. Ensure operational substance is maintained across global entities and that returns align with value‑creating activities. Tax Policy, Governance & Risk Management Monitor global tax developments—including BEPS, OECD Pillar Two, U.S. and EU tax law changes—and assess business impacts. Assist with audits and tax authority interactions, developing robust strategies to mitigate risk. R&D, Clinical & Manufacturing Incentives Identify and optimize global R&D, clinical trial, and biomanufacturing incentives across jurisdictions. Partner with R&D, Clinical Operations, and site‑selection teams to evaluate tax‑advantaged opportunities for manufacturing, and trial locations. Maintain documentation and evidence required to sustain tax incentives and credits. Tax Forecasting, Modeling & Executive Communication Develop long‑range tax forecasts incorporating pipeline progression, regulatory milestones, launch sequencing, pricing, royalties, and market access assumptions. Partner with Tax Accounting to evaluate ASC 740 implications and uncertain tax positions. Distill complex tax topics into clear insights for senior leadership and the Board. Leadership & Collaboration Manage external advisors to ensure strategic alignment and cost‑effective execution. Collaborate with Legal, R&D, Clinical, CMC, Supply Chain, FP&A, and Treasury to embed tax considerations into business decisions. Qualifications 10+ years of international tax planning experience with multinational, IP‑centric organizations; life sciences or oncology sector strongly preferred. Deep expertise in U.S. international tax rules, OECD frameworks, Pillar Two, BEPS, and global transfer pricing. Demonstrated experience with complex cross‑border structuring, M&A tax planning, IP migration, and value chain transformation. Strong understanding of global clinical trial operations, biologics/small‑molecule manufacturing, CDMO/CRO relationships, and commercialization models. Exceptional communication skills with the ability to influence senior executives. Advanced degree or certification preferred (JD/LLM/CPA/MST). Education Required: Bachelor's degree in Accounting, Finance, Tax, or related discipline. MBA or advanced business degree preferred. CPA required Core Competencies Strategic Thinking & Scenario Planning Executive Presence & Communication Cross‑Functional Influence & Collaboration Analytical & Problem‑Solving Skills Risk Management & Governance Team Leadership & Talent Development Supervisory Responsibilities: Lead a global tax team